Biomarkers of acute kidney injury in clinical laboratory / 中华检验医学杂志

ABSTRACT

Acute kidney injury ( AKI) is a common and serious clinical problem.Serum creatinine (SCr) and urine output are still used as the most common biomarkers for diagnosis of AKI.However, neither of them is an ideal indicator for diagnosis of AKI.In recent years , a number of potential biomarkers of AKI with more favorable test characteristics than SCr have been identified and studied in a variety of experimental and clinical settings.This review describes the novel biomarkers of AKI , including NGAL , IL-18, KIM-1, Cys C and L-FABP, which have now progressed to the clinical phase.