Determination of Related Substances in Dienestrol Tablets by HPLC / 中国药师
China Pharmacist
;
(12): 341-343, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-452835
ABSTRACT
Objective:
To determine the related substances in dienestrol tablets by HPLC.Methods:
The separation was performed on a C18 column(250 mm × 4. 6 mm,5μm). The mobile phase consisted of methanol-acetonitrile(76∶24), the flow rate was set at 0. 8 ml·min-1 with the detection wavelength at 229 nm, and the sample size was 10 μl.Results:
Under the established chromatographic conditions, the related substances and dienestrol were separated completely. The limit of detection was 2 ng.Conclusion:
The method is simple, accurate, specific and sensitive in the determination of related substances in dienestrol tablets.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2014
Tipo de documento:
Artigo
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