Relationship and Research Prospects of T Helper Cells and Aplastic Anemia / 浙江中医药大学学报
Journal of Zhejiang Chinese Medical University
; (6): 922-926, 2014.
Article
em Zh
| WPRIM
| ID: wpr-453280
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WPRO
ABSTRACT
Objective To review the pathogenesis and research prospects in AA.[Methods] In this paper, we summarize the imbalance mechanism of Th1/Th2, and the relationship of fol icular helper T cells(Tfh),Thl7, Th9 ,Th22 with aplastic anemia. [Results]The imbalance of Th1/Th2 cells leads to bone marrow failure. Immunosuppressive therapy can inhibit Th1 cell, restore the balance. The pathogenesis of Tfh, Thl7, Th9 and Th22 is closely correlated with AA. [Conclusion] AA pathogenesis is complex, CD4+cellsubsets is related to the occurrence and development of AA. Detect the levels of immune cells in the serum of patients is beneficial for diagnosis and treatment of AA.
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Idioma:
Zh
Revista:
Journal of Zhejiang Chinese Medical University
Ano de publicação:
2014
Tipo de documento:
Article