C-Kit-Negative Gastrointestinal Stromal Tumor in the Stomach
Journal of Gastric Cancer
; : 290-294, 2015.
Article
em En
| WPRIM
| ID: wpr-45379
Biblioteca responsável:
WPRO
ABSTRACT
C-kit-negative gastrointestinal stromal tumors (GISTs) are uncommon, and there have been few reports about the diagnosis and treatment of c-kit-negative GISTs in the stomach. We report the case of a patient who was diagnosed with a huge and atypical GIST in the stomach. The GIST was completely resected and finally diagnosed as c-kit-negative GIST based on immunohistochemical staining of tumor cells, which were negative for CD117 and CD34 and positive for Discovered on GIST-1 (DOG1). C-kit-negative GISTs could be treated by complete resection and/or imatinib, which is the same treatment for c-kit-positive GISTs.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Estômago
/
Proteínas Proto-Oncogênicas c-kit
/
Tumores do Estroma Gastrointestinal
/
Diagnóstico
/
Mesilato de Imatinib
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Journal of Gastric Cancer
Ano de publicação:
2015
Tipo de documento:
Article