Analysis of patients with ovarian cancer recurrence after treatment of lymph node regions alone and prognosis of survival / 中国基层医药

ABSTRACT

Objective To explore effects,survival and prognostic factors of regional lymph node recurrence of ovarian cancer patients after surgery in our hospital.Methods 1 348 cases of ovarian cancer in our hospital,regional lymph nodes filter out the postoperative recurrence alone were selected,44 cases were analyzed through a complete medical history,then the recurrence characteristics,treatment,prognosis,and prognostic factors were obtained.Results According to the disease,44 patients were treated with the second surgery,radiotherapy or chemotherapy,completed remission after treatment in 36 cases,some improvement in 7 cases,1 case,no significant improvement.44 patients 5-year cumulative survival rate was 65.32％,lymph node dissection adjuvant chemotherapy group,local radiotherapy and chemotherapy group,chemotherapy group cumulative survival difference were statistically significant (Kaplan-Meierx2 =23.685,P =0.000);may affect prognostic factors univariate Log-rank analysis showed that age,the recurrence time,the number of tumor recurrence and prognosis (x2 =11.254,9.254,15.625,all P ＜ 0.05) ; Cox regression analysis showed that age,time to recurrence,relapse foci were independent prognostic factors (P =0.000,0.006,0.000).Conclusion The patients with ovarian cancer recurrence after surgery alone has its unique regional lymph node characteristics,treatment should consider the factors affecting the prognosis.