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The applications of chromatin immunoprecipitation in the study on the downstream target genes of androgen receptor in prostate cancer cells / 中华检验医学杂志
Chinese Journal of Laboratory Medicine ; (12): 673-677, 2014.
Artigo em Chinês | WPRIM | ID: wpr-454672
ABSTRACT
Prostate cancer is one of the most common malignant tumor of male population in the West.Via binding to androgen response element in the genome and interacting with co-regulators,androgen receptor can participate in the development of prostate cancer and the convertion from androgen dependent prostate cancer to androgen independent prostate cancer.Chromatin immunoprecipitation ,coupled with PCR , chip,and high-throughput sequencing ,makes a huge progress in the study on the downstream target genes of androgen receptor and provide a new way to understand the molecular mechanisms of castration -resistant prostate cancer.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Laboratory Medicine Ano de publicação: 2014 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Laboratory Medicine Ano de publicação: 2014 Tipo de documento: Artigo