The applications of chromatin immunoprecipitation in the study on the downstream target genes of androgen receptor in prostate cancer cells / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 673-677, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-454672
ABSTRACT
Prostate cancer is one of the most common malignant tumor of male population in the West.Via binding to androgen response element in the genome and interacting with co-regulators,androgen receptor can participate in the development of prostate cancer and the convertion from androgen dependent prostate cancer to androgen independent prostate cancer.Chromatin immunoprecipitation ,coupled with PCR , chip,and high-throughput sequencing ,makes a huge progress in the study on the downstream target genes of androgen receptor and provide a new way to understand the molecular mechanisms of castration -resistant prostate cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Laboratory Medicine
Ano de publicação:
2014
Tipo de documento:
Artigo
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