Detection and significance of myocardial enzyme spectrum in premature infants with hyperbilirubinemia / 国际检验医学杂志

ABSTRACT

Objective To investigate the changes and clinical significance of myocardial enzyme spectrum in the premature in-fants with hyperbilirubinemia .Methods The myocardial enzymes spectrum (AST ,CK ,CK-MB) in 90 premature infants with hy-perbilirubinemia were tested and the detection results were analyzed .Then their comparison with the control group consisting of 27 premature infants was performed .Results The detection results of myocardial enzymes spectrum in the hyperbilirubinemia prema-ture infants were higher than those in the control group ,but only the increase of CK-MB had statistical significance (P<0 .05);the positive incidence rate of the myocardial enzymes in the hyperbilirubinemia premature infants was 55 .56% (50/90) ,which was ob-viously higher than 7 .41% (2/27) in the control group ,the difference had statistical significance (P<0 .01) .Conclusion Hyperbil-irubinemia in premature infants can cause the myocardial damage and has the high incidence rate .The myocardial enzyme spectrum should be routinely detected for guiding the clinical treatment in the premature infants with hyperbilirubinemia .