Thrombopoietin and acute radiation sickness / 国际药学研究杂志

ABSTRACT

Megakaryocytic hematopoietic disorders is one of the leading causes of death in patients with acute radiation sickness bleeding. Thrombopoietin (TPO),the main stimulation factor of megakaryocytopoiesis, can promote megakaryocytic hematopoietic recovery after radiation injury and increase peripheral platelet count. Early application of TPO after irradiation can play a key role in prevention and treatment of bleeding complications of acute radiation sickness. Studies have shown that TPO may have a stronger role in promoting hematopoiesis. In this paper, a brief overview of new progress on the TPO and acute radiation sickness is summarized.