Expression and therapy of Prame gene on hematologic malignancies / 国际肿瘤学杂志
Journal of International Oncology
; (12): 611-614, 2014.
Article
em Zh
| WPRIM
| ID: wpr-456220
Biblioteca responsável:
WPRO
ABSTRACT
As a member of the family of cancer-testis antigen,preferentially expressed antigen of mela-noma(Prame)can improve the proliferation of tumor via inhibiting the retinoic acid receptor signal path and impeding the transcription factor which is a wide range of physiological processes in development and differentia-tion of tumor cells. Prame expresses in solid tumors and hematological malignancies,which is widely used for tumor diagnosis,monitoring of tumor metastasis and immunotherapy.
Texto completo:
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Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2014
Tipo de documento:
Article