Drug resistance monitoring of Enterococcus faecalis and Enterococcus faecium in the hospital from 2009 to 2013 / 国际检验医学杂志

ABSTRACT

Objective To investigate the antimicrobial resistance of E.faecalis and E.faecium isolated from the Hospital from 2009 to 2013.Methods Minimum inhibitory concentration method was used for antimicrobial susceptibility test of the clinical iso-lates.Results were judged according to Clinical and Laboratory Standards Institute′s 2013 version of criterias.Results A total of 819 nonduplicated E.Faecalis and 726 nonduplicate E.faecium isolates were collected.The strains were still highly susceptible to linezolid and vancomycin,to which the drug-resistance rates were both less than 1.5%.The prevalence of vancomycin-resistant E. faecalis and E.faecium was 0.1% and 1.5%,respectively.The ratio of E.faecalis resistant to ampicillin,penicilin and nitrofuran-toin was 4.3%,1.6% and 1.6%,respectively.More than 87% E.faecium strains were resistant to ampicillin and penicillin,and the E.faecium strains were more resistant to most drugs tested than E.faecalis .Conclusion There was an obvious difference of anti-biotic resistance beween E.Faecalis and E.Faecium isolates.Therefore,Continuous monitoring the drug resistance is helpful to guide the clinical rational drug use.