Exploring in management of women with atypical squamous cells of undetermined significance / 实用医学杂志

ABSTRACT

Objective Exploring in processing method to triage of women with a cytologic smear showing atypical squamous cells of undetermined significance. Methods All 130 cases were diagnosed with ASCUS received high-risk HPV (hr-HPV)test, colposcopic inspections, reformeded Reid's colposcopic index score and cervical biopsies for pathological examination. Resluts The pathology of 130 ASCUS patients included 31cases of normal and inflammation (23.90%), 29 cases of CINⅠ(22.30%), 14 cases of CINⅡ(10.80%), 55 cases of CINⅢ or cervical carcinoma in situ (42.30%), and 1 case of invasive cervical carcinoma (0.80%). The reformed Reid's colposcopic index score of 130 ASCUS patients included 32 cases of 0 score (24.60%), 36 cases of 1~2 scores (27.70%), 47 cases of 3~4 scores(36.10%), 15 cases of 5~6 scores(11.60%). 2. The colposcopy used to detect the CIN of ASCUS, its sensitivity was 98.99%(98/99), specificity was 51.61%(16/31). The hr-HPV used to detect the CIN of ASCUS, its sensitivity was 96.97%(96/99), specificity was 32.26%(10/31). Conclusion Both the reformeded Reid′s colposcopic index score and hr-HPV testing as the clinical triage methods of ASCUS. The former has good sensitivity and specificity ,which is superior to hr-HPV testing.