Cord blood Cytokines on the Development of Cerebral Palsy in Premature Infant / 소아과
Korean Journal of Pediatrics
;
: 1293-1299, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-46070
ABSTRACT
PURPOSE:
This study was performed to determine the relation between cord blood plasma cytokines responses and development of cerebral palsies in premature infants.METHODS:
Interleukin-1beta(IL-1beta), Interleukin-6(IL-6), Tumor necrosis factor-alpha(TNF-alpha) were measured using ELISA kits in premature infants(n=60) who were admitted to St. Benedict Hospital from September 2001 to June 2003. Retrospective study was done by review of medical records.RESULTS:
Cord blood levels of IL-1beta, IL-6 and TNF-alpha in the cerebral palsy group were higher, especially IL-6 but were not significant, compared with the control group. Cord blood levels of IL-6 in the cerebral palsy without asphyxia, sepsis, PROM, RDS and pneumonia were significantly different, compared with the control group.CONCLUSION:
Cord blood levels of IL-1beta, IL-6 and TNF-alpha in the cerebral palsy group were increased, but concentrations of IL-6 increased significantly. Cord blood levels of IL-6 may be a useful value to predict the development of cerebral palsy, because they are related to IL-6 rather than to TNF-alpha & IL-1beta in this study.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paralisia
/
Plasma
/
Pneumonia
/
Asfixia
/
Recém-Nascido Prematuro
/
Ensaio de Imunoadsorção Enzimática
/
Paralisia Cerebral
/
Prontuários Médicos
/
Estudos Retrospectivos
/
Citocinas
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Recém-Nascido
Idioma:
Coreano
Revista:
Korean Journal of Pediatrics
Ano de publicação:
2004
Tipo de documento:
Artigo
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