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Clinical efficacy of central pancreatectomy and distal pancreatectomy:a Meta-analysis of the reserved endocrine and exocrine functions of the pancreas / 中国组织工程研究
Chinese Journal of Tissue Engineering Research ; (53): 322-328, 2015.
Artigo em Chinês | WPRIM | ID: wpr-461049
ABSTRACT

BACKGROUND:

Central pancreatectomy is a surgical treatment for tumors at the neck or the middle part of the pancreas, which can reserve more normal pancreas, not cut adjacent organs, and reduce the incidence of postoperative internal and external pancreatic secretion deficiency with respect to the expanded proximal and distal pancreatectomy.

OBJECTIVE:

To systematicaly evaluate the clinical efficacy of the central pancreatectomy and distal pancreatectomy.

METHODS:

A computer-based search of Chinese and English databases was performed, and then 15 controled clinical trials were included and systematicaly evaluated using RevMa5.2 software. RESULTS AND

CONCLUSION:

Totaly 1 079 cases were included in this study, which consisted of 436 central pancreatectomy cases and 643 distal pancreatectomy cases. Meta-analysis showed that compared with the distal pancreatectomy group, the incidences of postoperative pancreatic fistula and complications were significantly higher, the risk of postoperative endocrine and exocrine insufficiency were significantly lower, while the surgical time (SMD 59.23, 95%CI 22.41-96.05, P < 0.01) and hospital stays (SMD 7.01, 95%CI 1.94-12.09,P< 0.01) were longer in the central pancreatectomy group. These findings indicate that although the central pancreatectomy has a high postoperative complication incidence, it can be accepted clinicaly, which may be a reasonable operation method to preserve pancreatic exocrine and endocrine function.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Revisões Sistemáticas Avaliadas Idioma: Chinês Revista: Chinese Journal of Tissue Engineering Research Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Revisões Sistemáticas Avaliadas Idioma: Chinês Revista: Chinese Journal of Tissue Engineering Research Ano de publicação: 2015 Tipo de documento: Artigo