Diagnostic Value of Contrast-enhanced US for Kidney Tumor:A Meta-analysis / 中国医学影像学杂志

ABSTRACT

Purpose To review English and Chinese literatures on diagnosing kidney tumor using contrast enhanced ultrasound (CEUS). Materials and Methods CEUS and kidney tumor were selected as the key words to search CNKI, Wanfang data, CBMDisc, VIP, Embase, the Cochrane Library and PubMed from March 2009 to March 2014. According to evidence-based medicine requirements, heterogeneity test and quality evaluation were performed to evaluate the literature that met the inclusion criteria. The pooled sensitivity, specificity and diagnostic odds ratio (DOR) of included literature were calculated to determine summery receiver operating characteristic curve (SROC), and calculated the area under the curve (AUC) as well as Q index. Results A total of 12 studies met the inclusion criteria, including 9 in Chinese and 3 in English. Heterogeneity test showed a low heterogeneity among the literature, thus fixed effect models used. The pooled sensitivity was 0.95 (95%CI 0.93-0.96), specificity was 0.79 (95%CI 0.73-0.84), DOR was 76.36 (95%CI 41.73-139.71), Q index was 0.9208, and SROC AUC was 0.9706. Conclusion CEUS has high diagnostic value and accuracy for kidney tumors, which can provide imaging information for clinical decision.