Adipokines and colorectal cancer / 国际肿瘤学杂志

ABSTRACT

Adipocytokines included adiponectin,leptin,omentin and visfatin are secreted by adipocytes and closely associated with obesity and insulin resistance.Many studies find that these adipocytokines are correlated with the occurrence and development of colorectal cancer,and may be promising biomarkers with respect to clinical diagnosis and prognosis of colorectal cancer.At present,the occurrence mechanisms of colorectal cancer induced by adipocytokines are unclear and needed to be extensively explored.