The change of target area and the surrounding structure during the intensity modulated radiotherapy of nasopharyngeal carcinoma / 国际肿瘤学杂志

ABSTRACT

Intensity modulated radiation therapy(IMRT)has become the mainstay of treatment modal-ity for nasopharyngeal carcinoma(NPC). The whole treatment course generally continues 7 to 8 weeks. With the radiotherapy proceeding,the patients exhibit oropharyngeal reaction aggravating,weight losing and tumor shrinking,resulting in the changes of tumor target and surrounding tissue. Those changes may influence the dose distribution of tumor and organ at risk. It is necessary to modulate target volume during radiotherapy of NPC.