Clinical and laboratory investigation of hematological malignancies with t(11;19)(q23;p13.1) / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 58-60, 2015.
Article
em Zh
| WPRIM
| ID: wpr-465833
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the clinical and laboratory characteristics of hematological malignancies with t(1 1;19)(q23;p13.1).Methods Chromosome specimens of bone marrow cell from a patient with hematological malignancy were collected.After short-term culture,and chromosome karyotype analysis was carried out by R banding technique.Results The chromosome karyotype of the patient diagnosed with AML M4+ was t (11;19)(q23;p13.1).The patient did not obtain complete remission after application of MA regimen chemotherapy.Conclusions t(11;19)(q23;p13.1) translocation is a rare and recurring chromosome abnormality,which is related with a specific type of AML.The prognosis of the AML patients with this chromosome abnormality is poor.
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Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Leukemia & Lymphoma
Ano de publicação:
2015
Tipo de documento:
Article