Application of velocity vector imaging and dobutamine stress echocardiography in evaluating the strain of left ventricular in the long axis views in diabetic patients with LVEF ＞50％ / 中华超声影像学杂志

ABSTRACT

Objective To assess the systolic strain of left ventricular(LV) in the long axis views in diabeties mellitus(DM) patients with LVEF value ＞ 50％ with velocity vector imaging (VVI) and dobutamine stress echocardiography (DSE).Methods Thirty DM patients,which were excluded from coronary artery disease,valvular heart diseases,congenital heart diseases,hypertension,and LVEF value ＞50％ by echocardiography,and 20 volunteers with age and sex matched were involved in the study.Two-dimensional VVI echocardiographic cine loops were stored at baseline and dobutamine stress in the apical four-chamber,two-chamber and long axis views of LV.The maximum long systolic velocity (Vs),strain (ε)and strain rate (SR) were obtained from sygno VVI software.Results The Vs,ε and SR decreased from basal to apical in the LV walls whether in the control group or in the DM group.At baseline,SR in 7 segments,ε in 4 segments and Vs in 3 segments in the DM group decreased significantly than those in the control group (P ＜0.05).After the maximum dobutamine stress,all parameters decreased significantly in the DM group than those in the control group (all P ＜0.05).In addition,67％ parameters in apical LV and 11％ parameters in middle LV in the DM group were lower than those in the control group.All parameters in basal LV were comparable between the two groups at baseline.Conclusions The Vs,ε and SR showed decreased tendency from basal to apical in the long axis of LV.The Vs,ε and SR impairment in the long axis of DM patients appeared first in apical tissue of LV.DSE could increase the sensitivity of VVI parameters in the earlier stage.