Neuroprotective effect of citicoline on ischemic stroke / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 700-703, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-466498
ABSTRACT
Recent experimental ischemic stroke studies have shown that citicoline can not only have neuroprotective effect,but also play the effect of nerve repair by increasing the number of endothelial progenitor cells in peripheral blood,promoting angiogenesis and neurogenesis,and enhancing neuronal plasticity.So far,although the multicenter randomized placebo controlled trials with the largest sample sizethe International Citicoline Trial on Acute Stroke (ICTAS) has obtained a neutral result,the subgroup analyses have shown that citicoline treatment is more effective than placebo of not receiving rtPA thrombolytic therapy,and does not have obvious adverse reaction.Therefore,its application in patients with acute ischemic stroke is reasonable,particularly in those not receiving thrombolytic therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Chinês
Revista:
International Journal of Cerebrovascular Diseases
Ano de publicação:
2014
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS