Self-renewal mechanism of cancer stem cells / 国际肿瘤学杂志

ABSTRACT

Cancer stem cells comprise a sub-population with the capacity of self-renewal,self-differentiation and high tumorigenicity.Cancerogenesis,development,relapse and therapeutic resistance are closely related with these cells.The most important characteristics of these cells are the ability to self-renew.So insight into the regulating mechanism of self-renewal in cancer stem cells will be important for the development of novel molecular agents targeted the cancer stem cells.