LASS family and tumor / 国际肿瘤学杂志

ABSTRACT

LASS gene family is a group of highly conserved and longevous gene LASS protein has a ceramide synthase activity,which can synthesize different types of ceramides.Ceramide is a key intermediate in tumor cells growth,signal transduction and other aspects.Thus it is inferred that the expression of LASS gene can suppress the occurrence and development of tumor within a certain range.