The result comparisons of partial prethrombotic state indexes between patients with metastatic gastrointestinal malignant tumor and with non-metastatic gastrointestinal malignant tumor / 国际检验医学杂志

ABSTRACT

Objective To observe the levels of von willebrand factor (vWF) ,antithrombin (AT) ,D‐dimer (DD) and tissue fac‐tor procoagulant activity (TF‐PCA) on patients with malignant gastrointestinal tumor and then make comparisons .Methods Use machine to detect the vWF、AT、DD and TF‐PCA levels of 50 patients with metastatic gastrointestinal malignant tumor (group C) and another 59 patients with non‐metastatic gastrointestinal malignant tumor (group B) ,and then compare them with those 60 cases of normal physical examination people (group A) .Results Compared with group A ,the levels of vWF、DD and TF‐PCA showed obvious increases (P0 .05) .Conclusion Patients with malignant gastrointestinal tumor have imbalance in coagulation and fibrinolysis system ,and this imbalance is much more obvious in metastatic tumor than non‐metastatic tumor .The prethrombotic state indexes of patients are only correlated to gas‐trointestinal malignant tumor ,but not to the parts where the tumor is in .Therefore ,the detection of vWF、AT、DD and TF‐PCA lev‐els can provide reference for the condition monitoring and prognosis of gastrointestinal malignant tumor .