Study of cytogenetic characteristics on myelodysplastic syndrome and acute myeloid leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
; (12): 105-107, 2012.
Article
em Zh
| WPRIM
| ID: wpr-473346
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WPRO
ABSTRACT
ObjectiveTo evaluate the cytogenetic characteristics of the patients with acute myelomonocytic leukemia (AML-M4), acute monocytic leukemia (AML-M5)and myelodysplastic syndrome (MDS).MethodsChromosomes of bone marrow cells were prepared by short-term culture.Karyotype analysis was performed in 100 AML-M4,46 AML-M5 and 115 MDS by R-banding technique.Results26 % (26/100) AML-M4 had clonal cytogenetic abnormalities which mainly include +8,t(8;21) and -7.26 % (12/46) AML-M5 had clonal cytogenetic abnormalities which mainly include +11. 39 %(45/115)had clonal cytogenetic abnormalities which mainly include +8, Hypodiploid and -7. ConclusionCytogenetic detection is very important for the diagnosis of myelodysplastic syndrome and acute myelocytic leukemia.
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WPRIM
Idioma:
Zh
Revista:
Journal of Leukemia & Lymphoma
Ano de publicação:
2012
Tipo de documento:
Article