Effect of budesonide and doxofylline on patients with moderate persistent asthma / 实用医学杂志

ABSTRACT

Objective To observe the effect of budesonide/doxofylline on patients with persistent asthma. Methods Sixty patients with moderate asthma were randomly divided into treatment group and control group. Patients in treatment group accepted the inhalation budesonide 400μg/d and doxofylline tablet 0.2 bid po but those in control group accepted the inhalation budesonide/formoterol 160/4.5μg bid. FeNO, sputum eosinophils, PEF and ACT scores were compared between two groups. Results PEF and ACT scores in treatment group were lower to those in control group (P0.05). After three months, sputum eosinophils in treatment group were better than that in control group (P0.05). Conclusion There is no significant difference in controlling asthma between budesonide/doxofylline and budesonide/formooterol