Bioinformatics prediction on glutathione S-transferase antigen epitopes of Echinoccocus granulosus / 国际检验医学杂志
International Journal of Laboratory Medicine
; (12): 1818-1820, 2015.
Article
em Zh
| WPRIM
| ID: wpr-473958
Biblioteca responsável:
WPRO
ABSTRACT
Objective To analyse the secondary structure of glutathions S-transferase of Echinoccocus granulosus(EgGST)and predict the B cell and T cell epitopes with informatics tools,in order to provide basic data and references for the following design of epitope vaccine.Methods The B cell and T cell epitopes of EgGST were predicted by DNAstar,Biosun software and Propred MHC class-Ⅱ Binding Peptide Prediction Server software.Results Many distinct antigenic epitopes of EgGST were identified by comput-er,there existed 8 B cell epitopes and 7 T cell epitopes.Conclusion Analysis of predicted epitopes of EgGST antigenic might be sig-nificant for future research of epitope vaccine.
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1
Índice:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
International Journal of Laboratory Medicine
Ano de publicação:
2015
Tipo de documento:
Article