The research progress of myocardial perfusion agent with 99TcmN core / 中华核医学与分子影像杂志

ABSTRACT

Radionuclide MPI is an important noninvasive modality for the diagnosis of coronary artery disease.The current clinically useful MPI tracers,201Tl and 99Tcm labeled agents,have limitations.Some known ligands bound with 99TcmN core might be promising MPI agents because of their high chemical stability.This review summarizes the structure,biodistribution and imaging characteristics of the 99TcmN core labelled MPI tracers with emphasis on several agents having promising prospects for future applications.