The value of joint detection serum Cysc and Hcy for early diagnosis of diabetic nephropathy / 国际检验医学杂志

ABSTRACT

Objective The text is to discuss the value of joint detection of serum cystatin C(CysC)and homocysteine(Hcy)in early diagnosis of diabetic nephropathy.Methods According to the Urine Trace Albumin Excretion Rate (UAER),divided 120 dia-betic patients to pure diabetic patient group and early-stage diabetic patient group,and 60 healthy cases was chosen in our hospital as control group.The concertration of serum CysC and Hcy in every group was tested,and the results were statistically analyzed. Results The result of serum CysC and Hcy in pure diabetic patient group and early-stage diabetic patient goup was higher than control group (P <0.05),and the concertration of serum CysC and Hcy was increased with the progress of the diabetic nephropa-thy significantly (P <0.05),the positive rate of joint detection serum CysC and Hcy in diabetic nephropathy was 86.7%,signifi-cantly higher than that of the two separate positive rate of detection.Conclusion Joint detection serum CysC and Hcy for diagnosis of early diabetic nephropathy has certain good value,Is worth the clinical promoted.