Correlation between CD4+CD29+T cells and the pathological typing and staging for patients with primary pulmonary carcinoma / 实用医学杂志

ABSTRACT

Objective To explore the correlation between CD4+CD29+T cells and the pathological typing and staging for patients with primary pulmonary carcinoma. Methods Flow cytometry was used to detect peripheral blood CD4+CD29+T cells, gamma interferon (IFN-γ) and tumor necrosis factor alpha (TNF-α) of 60 patients with lung cancer. The relationships between them and the pathological typing and staging were studied. Results (1) The CD4+CD29+T cellsand TNF-α percentages in thecancer patients were significantly higher than those of the control group (P 0.65, P < 0.05). Conclusion Theincreased CD4+CD29+T cells and TNF-α, together with decreased IFN-γ arehighly indicative of immunological characteristics of lung cancer , and closely related to the pathological typing and staging.