Advance in Research of Biomarkers of Spinal Cord Injury (review) / 中国康复理论与实践

ABSTRACT

Various functional proteins are differently expressed in each pathologic stage after spinal cord injury, representing injury and the pathological change of repair. Ideal biomarker is helpful to evaluate complicated biological reactions of spinal cord injury and predict prognosis. As specific serum markers of central nerve injury, neuron-specific enolase (NSE) and astrocyte primary calcium binding protein S-100βhad been studied preliminarily, but the specificity and sensitivity need more research. Future efforts still need to develop ideal bio-markers to predict functional outcome.