Apocrine Carcinoma of the Axilla with Predominant Signet Ring Cell Features A Case Report
Korean Journal of Pathology
;
: 326-328, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-47954
ABSTRACT
Apocrine carcinoma arising from the apocrine sweat glands is a rare cutaneous malignant tumor which occurs predominantly in the axilla of elderly individuals. The typical histologic features of apocrine carcinoma is within a well developed glandular lumina with abundant eosinophilic cytoplasm and evidence of decapitation secretion. In rare instances, predominant signet ring cell features in apocrine carcinoma has been reported. We experienced a case that occured in the right axilla of a 59-year-old. Histopathologic examination showed a solid tumor that extended from the upper dermis into the subcutis, with a delicate infiltrate of epithelial cells. The cells had granular amphophilic cytoplasm, predominantly showed distinct signet ring cell morphology, and were strongly positive for epithelial mucin. Both lysozyme and gross cystic disease fluid protein-15 were identified in the tumor cells. We diagnosed this to be a case of primary signet ring cell apocrine carcinoma of the axilla after several immunohistochemical and clinical evaluations.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Glândulas Apócrinas
/
Axila
/
Glândulas Sudoríparas
/
Muramidase
/
Carcinoma de Células em Anel de Sinete
/
Derme
/
Citoplasma
/
Decapitação
/
Eosinófilos
/
Células Epiteliais
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pathology
Ano de publicação:
2011
Tipo de documento:
Artigo
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