The expression of odontoblast relevant proteins in dental pulp stem cells induced by BMP-7 / 实用口腔医学杂志
Journal of Practical Stomatology
;
(6): 753-756, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-479711
ABSTRACT
Objective:
To examine the expression of odontoblast related proteins in dental pulp stem cells(DPSCs)induced by BMP-7.Methods:
DPSCs were cultured in the common culture medium or medium supplemented with 1 00 ng/ml BMP-7.Electron microscope,CCK8 and immunohistochemical staining were carried out to estimate the cell morphology and differentiation.Results:
In-duced by BMP-7,the morphology of DPSCs was not changed,the proliferation of DPSCs was slower than that of the cells without BMP-7 treatment.DPSCs were negative for the expression of DSPP,DMP-7 and ALP.However,DPSCs were found strongly positive for DSPP,DMP-7 and ALP after the induction of BMP-7.Conclusion:
BMP-7 induction may promote the differentiation of DPSCs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Practical Stomatology
Ano de publicação:
2015
Tipo de documento:
Artigo
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