Clinical observation of serum gastrin and the plasma motilin levels in 80 patients with primary bile reflux gastritis / 中国基层医药

ABSTRACT

Objective To observe the changes of serum gastrin (GAS)and plasma motilin (MTL)in patients with primary bile reflux gastritis.Methods 80 patients with primary bile reflux gastritis were selected.The serum GAS and plasma level of MTL were observed,and the results were compared with 80 healthy people.Results The content of MTL in plasma of the study group (282.37 ±31.56)pg/mL was significantly lower than that in the control group (t =-21.352,P <0.01).The level of serum GAS (91.28 ±27.71)pg/mL was significantly higher than the control group (t =-28.388,P <0.01).Conclusion Compared with the healthy people,secretion of MTL in patients with primary bile reflux gastritis has insufficient phenomenon,and has the excessive secretion of GAS in the body,this may be a factor in the pathogenesis of the disease.