Correlation analysis and treatment of laryngopharyngeal relfux disease with anxiety and depression sympoms / 中国耳鼻咽喉头颈外科

ABSTRACT

[ABSTRACT]OBJECTIVETo observe the correlation of laryngopharyngeal reflux disease(LPRD) with anxiety and depression symptoms, and to study the treatment efficacy.METHODSThe clinical data of 98 cases with LPRD were retrospectively analyzed from March 2014 to December 2014. According to the result of the Hospital Anxiety and Depression Scale(HADS) scores, 56 cases were normal and 42 cases were abnormal. The abnormal group were randomly divided into treatment group(21 cases) and control group(21cases).The control group and normal HADS group were treated by omeprazole capsules, treatment group was given omeprazole capsules and flupenthixol melitracen tablets with psychological adjustment.RESULTS The effective rate of treatment group and control group was 66.67% and 14.29% respectively, the difference was statistically significant(χ2=11.958,P0.05).CONCLUSION Laryngopharyngeal reflux in some patients exist state of anxiety or depression. Individualized treatment in patients with laryngopharyngeal reflux can improve the efficacy.