The correlation analysis of amplitude-integrated electroencephalogram and magnetic resonance imaging in infants with hypoxic-ischemic encephalopathy / 中国医师进修杂志

ABSTRACT

Objective To investigate the correlation analysis of amplitude-integrated electroencephalogram (aEEG) and magnetic resonance imaging (MRI) in infants with hypoxic-ischemic encephalopathy (HIE) to early evaluate the severity of HIE.Methods Ninety term infants with HIE were selected.They were detected by aEEG within 12 hours after birth,and accepted cranial MRI 3 to 7 days after birth.The infants were divided into 3 groups (aEEG normal,mild abnormality and severe abnormality) according to the result of aEEG.The Spearman correlation analysis was completed in infants with HIE between aEEG clinical grading and cranial MRI grading.Results In 90 infants with HIE,the clinical gradingmild HIE 44 cases (48.9％),midrange HiE 29 cases (32.2％) and severe HIE 17 cases (18.9％).Cranial MRI gradingmild 49 cases (54.4％),midrange 23 cases (25.6％) and severe 18 cases (20.0％).The result of aEEGaEEG normal 43 cases (47.8％),aEEG mild abnormality 25 cases (27.8％) and aEEG sever abnormality 22 cases (24.4％).The result of correlation analysis showed that aEEG grading was positive correlation with the HIE clinical grading (r =0.970 7,P ＜ 0.01) and MRI grading (r=0.933 5,P ＜ 0.01).Conclusion The aEEG can early evaluate the severity of HIE.