Correlation between SCC antigen and the prognosis of cervical cancer patients following concurrent chemoradiotherapy / 부인종양
Korean Journal of Gynecologic Oncology
;
: 123-132, 2005.
Artigo
em Coreano
| WPRIM
| ID: wpr-48219
ABSTRACT
OBJECTIVE:
The aim of this study was to determine the correlation between SCC Ag and the prognosis in cervical cancer patients following concurrent chemoradiotherapy (CCRT).METHODS:
The charts of 116 patients following concurrent chemoradiotherapy among 330 patients diagnosed to cervical cancer at Yonsei University Medical Center from Jan. 1998 to June 2003 were reviewed retrospectively. Clinical characteristics (age, parity, body mass index), stage, lesion size, cell type, squamous cell subtype, initial SCC Ag (or=1.5), posttreatment SCC Ag (or=1.5) was evaluated with overall survival. Distribution of SCC Ag level before CCRT in relation to FIGO stage and failure pattern in SCC positive patients before CCRT were reviewed. Overall survival was estimated according to respectively, subgroups of initial SCC Ag, SCC Ag after 2nd CCRT and posttreatment SCC Ag. Chi square test and Kaplan Meier test were used for statistical analysis (P<0.05).RESULTS:
Overall survival was significantly correlated with only stage (P=0.0014). Two patients (15.4%) among 13 patients with recurrence had SCC Ag<1.5. Subgroups (1.5CONCLUSION:
The measurements of the levels of initial SCC Ag, SCC Ag after 2nd CCRT and posttreatment SCC Ag are expected to be useful in predicting the prognosis of the patients with cervical cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paridade
/
Prognóstico
/
Recidiva
/
Neoplasias do Colo do Útero
/
Estudos Retrospectivos
/
Tamanho Celular
/
Centros Médicos Acadêmicos
/
Estimativa de Kaplan-Meier
/
Quimiorradioterapia
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gynecologic Oncology
Ano de publicação:
2005
Tipo de documento:
Artigo
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