Usefulness of Colored 3D Imaging of Respiratory Impedance in Asthma
Allergy, Asthma & Immunology Research
;
: 322-328, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-48230
ABSTRACT
PURPOSE:
Recently, the clinical application of the forced oscillation technique (FOT) has progressed with the spread of commercially available FOT devices, including the impulse oscillation system and MostGraph. We investigated the usefulness of color 3D imaging of respiratory impedance in asthma using MostGraph.METHODS:
Whole-breath and within-breath respiratory system resistance (Rrs) and reactance (Xrs) were measured in 78 patients with asthma. Color 3D images were classified into three patterns the chronic obstructive pulmonary disease (COPD)-like pattern (high values of Rrs and Xrs with a marked respiratory cycle and frequency dependence), the asthma pattern (moderately high Rrs over the entire frequency and a respiratory cycle with slight Xrs changes), and a normal-like pattern (low Rrs and Xrs with few within-breath changes). The classification was performed by three researchers, who were unaware of the clinical information, and the clinical characteristics were compared among the three groups.RESULTS:
Color 3D imaging provided a COPD-like pattern in 25 patients, an asthma pattern in 39 patients, and a normal-like pattern in 14 patients. Patients with the COPD-like pattern were predominantly female with a higher body mass index, lower forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), and higher Rrs and Xrs values (whole-breath and within-breath variation). Those with the normal pattern had higher FEV1 and FVC, and a lower single-breath nitrogen washout slope. There were no differences in asthma control or exhaled nitric oxide levels among the three groups.CONCLUSIONS:
These results suggest that color 3D imaging of respiratory impedance may show asthma phenotypes.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fenótipo
/
Sistema Respiratório
/
Asma
/
Índice de Massa Corporal
/
Capacidade Vital
/
Volume Expiratório Forçado
/
Impedância Elétrica
/
Doença Pulmonar Obstrutiva Crônica
/
Óxido Nítrico
/
Nitrogênio
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Allergy, Asthma & Immunology Research
Ano de publicação:
2013
Tipo de documento:
Artigo
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