Relationship between anemia before radiotherapy and prognosis of patients with esophageal carcinoma / 肿瘤研究与临床

ABSTRACT

Objective To analysis the prognosis of esophageal carcinoma patients with anemia before radiotherapy. Methods 137 patients with esophageal carcinoma treated with three-dimensional conformal radiation therapy (3D-CRT) in the Second Peopleˊs Hospital of Jiaozuo over the past five years were retrospectively analyzed. There were 40 patients with anemia and 97 cases without anemia before radiotherapy. The prognosis of patients with anemia and the relationship with other clinical factors were evaluated by survival analysis. Results The 3-year and 5-year overall survival (OS) rates in non-anemic group were 43.6 % and 35.7 %, respectively, and 21.0 % and 16.4 % in anemic group. The 3-year and 5-year disease-free survival (DFS) rates in non-anemic group were 38.5 % and 25.3 %, respectively, and 13.1 % and 9.2 %in anemic group. The Kaplan-Meier method showed that both 3-year and 5-year OS and DFS rates in non-anemic group were significantly higher than those in anemic group (P< 0.05). Conclusion Anemia is the independent prognostic factor for patients with esophageal carcinoma in many clinical factors.