Correlation of H-type hypertension with serum uric acid and fibrinogen in the elderly / 中华老年医学杂志

ABSTRACT

Objective To discuss the correlation of high homocysteine (Hcy) hypertension (Htype hypertension) with serum levels of uric acid (UA) and fibrinogen (FIB) in the elderly.Methods A total of 188 elderly in-and out-patients with essential hypertension were selected in our heart medicine outpatient and ward from April 2013 to April 2014.They were divided into H type hypertension group (n =136,Hey value≥ 10μmol/L) and primary hypertension group (n =52,Hcy value＜10μmol/L).Another 160 elderly individuals without hypertension taking physical examination in our hospital during same period served as controls.General information were colleted,and the serum Hcy,UA and FIB were detected in all the patients to compare the differences among different groups.Logistic regression analysis was adopted to seek affecting factors of H-type hypertension patients.Results Compared with control group,there were statistical increases in the levels of UA and FIB for primary hypertension group and H-type hypertension group(P＜0.01).Compared with primary hypertension group,there were statistical differences in the level of UA and FIB(P＜0.01).The influence factors analysis showed that H-type hypertension was positively correlated with the serum level of UA and FIB(P＜0.01).Conclusions H-type hypertension is closely associated with UA and FIB.It's good for management of hypertension patients to monitor UA and FIB levels.