Efficacies of topical timolol maleate eye drops for infantile superficial hemangiomas during proliferative phase / 中华全科医师杂志

ABSTRACT

To explore the therapeutic value of topical timolol maleate eye drops for infantile superficial hemangiomas.From March 2013 to May 2014,a total of 98 patients of infantile superficial hemangiomas during proliferative phase were divided into treatment (n =68) and control (n =30) groups.Topical smearing of timolol maleate eye drops was applied on tumor with a wet cotton swab.The effective rate of tumor shrinkage and the rate of color improvement for treatment group were better than those for control group (88％ vs.10％ ; 90％ vs.10％,both P ＜ 0.05).And the differences had statistical significance.Topical application of timolol maleate eye drops is both safe and efficacious for infantile superficial hemangiomas during proliferative phase.