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Serious Adverse Transfusion Reactions Reported in the National Recipient-Triggered Trace Back System in Korea (2006-2014)
Annals of Laboratory Medicine ; : 335-341, 2016.
Artigo em Inglês | WPRIM | ID: wpr-48337
ABSTRACT

BACKGROUND:

Adverse transfusion reactions (ATRs) are clinically relevant to patients with significant morbidity and mortality. This study aimed to review the cases of ATR reported in the recipient-triggered trace back system for a recent nine-year period in Korea.

METHODS:

Nine-year data obtained from 2006 to 2014 by the trace back system at the Division of Human Blood Safety Surveillance of the Korean Centers for Disease Control (KCDC) were reviewed. The suspected cases were assessed according to six categories (i) related to, (ii) probably related to, (iii) probably not related to, (iv) not related to transfusion, (v) unable to investigate, and (vi) under investigation.

RESULTS:

Since 2006, 199 suspected serious ATRs were reported in hospitals and medical institutions in Korea, and these ATRs were reassessed by the division of Human Blood Safety Surveillance of the KCDC. Among the reported 193 cases as transfusion related infections, hepatitis C virus (HCV) infection (135, 67.8%) was reported most frequently, followed by hepatitis B virus (HBV) infection (27, 13.6%), HIV infection (13, 6.5%), syphilis (9, 4.5%), malarial infection (4, 2.0%), other bacterial infections (3, 1.5%), HTLV infection (1, 0.5%), and scrub typhus infection (1, 0.5%), respectively. Of the 199 cases, 13 (6.5%) cases were confirmed as transfusion-related (3 HCV infections, 3 malarial infections, 1 HBV infection, 2 Staphylococcus aureus sepsis, 3 transfusion-related acute lung injuries, and 1 hemolytic transfusion reaction).

CONCLUSIONS:

This is the first nationwide data regarding serious ATRs in Korea and could contribute to the implementation of an effective hemovigilance system.
Assuntos

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Transfusão de Sangue / Infecções por HIV / Estudos Retrospectivos / Hepatite C / Lesão Pulmonar Aguda / República da Coreia / Reação Transfusional / Malária Tipo de estudo: Estudo observacional Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Annals of Laboratory Medicine Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Transfusão de Sangue / Infecções por HIV / Estudos Retrospectivos / Hepatite C / Lesão Pulmonar Aguda / República da Coreia / Reação Transfusional / Malária Tipo de estudo: Estudo observacional Limite: Humanos País/Região como assunto: Ásia Idioma: Inglês Revista: Annals of Laboratory Medicine Ano de publicação: 2016 Tipo de documento: Artigo