The therapeutic efficacy of middle- and low-dose methylprednisolone combined with methotrexate and selenium yeast on Graves ophthalmopathy / 中华内分泌代谢杂志

ABSTRACT

[Summary] The efficacy of the combining therapy of methylprednisolone and methotrexate on the Graves ophthalmopathy ( GO) was observed. Whether selenium supplement is beneficial based on this combining therapy scheme was evaluated. The results showed that the combining therapy of methylprednisolone and methotrexate was effective for the patients with moderate-to-severe GO. Selenium supplement did not further improve the remission of GO.