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Comparison of ultrasound weighted score and shear wave elastography in differentiating benign and malignant thyroid nodules / 中华超声影像学杂志
Chinese Journal of Ultrasonography ; (12): 1043-1046, 2015.
Artigo em Chinês | WPRIM | ID: wpr-484391
ABSTRACT
Objective To evaluate the diagnostic efficacy of shear wave elastography and ultrasound weighted score in differentiating benign and malignant thyroid nodules.Methods Ninety-two patients with 1 13 thyroid nodules (72 benign and 41 malignant)underwent ultrasound weighted score.The items and scores were as followhypoechogenicity(2),irregular margin(2),no well-defined border(1),no uniform and complete acoustic halo (1 ),microcalcification (2 ),anteroposterior to transverse diameter ratio ≥ 1 with irregular margin(6 ),nodules with cystic components which had an diameter larger than 5 mm (- 6 ), posterior enhanced echo(-2),metastasis of neck lymph nodes(6).Shear wave velocity(SWV)of thyroid nodules were measured by virtual touch tissue quantification and the mean SWV of five data was calculated. The diagnostic efficacy of shear wave elastography,ultrasound weighted score,and their combination in differentiating benign and malignant thyroid nodules were calculated by ROC curves.The diagnostic sensitivity,specificity,and accuracy of ultrasound scores,SWV,and their combination in differentiating malignant and benign thyroid nodules were compared.Results The ultrasound score cut-off for the diagnosis of malignant lesions was 4.5 with a sensitivity of 80.5%,specificity of 86.1 %,and accuracy of 84.1 %.The SWV cut-off for the diagnosis of malignant lesions was 2.55 m/s with a sensitivity of 70.7%, specificity of 88.9%,and accuracy of 82.3%.When two methods were combined,the diagnostic sensitivity, specificity,and accuracy were 95.1 %,80.6% and 85.8%,respectively.Comparing the sensitivity,specificity and accuracy of the three methods,there were no significant difference between any two methods (P >0.016 7),except that the sensitivity of combination was significantly higher than that of SWV (P <0.016 7).Conclusions Shear wave elastography and ultrasound weighted score both have high value in differentiating benign and malignant thyroid nodules.Combining two methods can not improve diagnosis value comparing with conventional ultrasonography.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Ultrasonography Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Chinese Journal of Ultrasonography Ano de publicação: 2015 Tipo de documento: Artigo