The clinical significance of monitoring of coagulation and fibrinolysis related indexes after hip replacement for preventing and diagnosing lower extremity deep venous thrombosis / 国际检验医学杂志

ABSTRACT

Objective To evaluate the clinical significance of monitoring of D‐dimer ,fibrinogen and fibrin degradation products after hip replacement for diagnosing and preventing the lower extremity deep venous thrombosis .Methods A total of 66 cases of patients who carried out hip replacement from April 2013 to April 2015 in the department of orthopaedic in this hospital were se‐lected .Patients complicated with lower extremity deep venous thrombosis were enrolled into the observation group ,while patients without lower extremity deep venous thrombosis were enrolled into the control group .Levels of D‐dimer ,fibrinogen and fibrin deg‐radation products were strictly monitored after hip replacement and were comparatively analysed .Results There were no statisti‐cally significant differences in levels of fibrinogen and fibrin degradation products between the two groups (P>0 .05) ,while statisti‐cally significant difference was found in level of D‐dimer between the two groups(P<0 .05) .Conclusion The monitoring of D‐di‐mer ,fibrinogen and fibrin degradation products after hip replacement could have clinical significance for diagnosing and preventing lower extremity deep venous thrombosis .