Analysis on risk factors of nosocomial infection of imipenem resistant Acinetobacter and investigation on class Ⅰ integron / 国际检验医学杂志

ABSTRACT

Objective To investigate the risk factors of nosocomial infection of imipenem‐resistant Acinetobacter and prevalence situation of class Ⅰ integron to provide references for preventing and controlling its nosocomial infection .Methods The strains of imipenem‐resistant Acinetobacter causing nosocomial infection were performed the drug resistance analysis and multivariate re‐search .The class Ⅰ integron gene was detected by using PCR .Results Admission to ICU ,joint use of antibacterial agents and high APACHEⅡ score were the independent risk factors of nosocomial infection induced by imipenem resistant Acinetobacter .The posi‐tive rate of class Ⅰ integron was up to 98 .6% .Conclusion The nosocomial infection of imipenem‐resistant Acinetobacter is affect‐ed by multiple factors .The class Ⅰ integron is widely prevalent in this hospital ,which is associated with the multidrug resistance of imipenem‐resistant Acinetobacter .The infection prevention measures in severe patients should be strengthened for timely finding the infection source ,protecting the susceptible populations and cutting off dissemination approach .