DNA methylation and asthma / 国际儿科学杂志

ABSTRACT

Bronchial asthma,a complex genetic disease,is influenced by environmental factors.As a connection of genetic susceptibility factors and environmental factors,the role of epigenetics in the pathogenesis of bronchial asthma is attracting more attention.DNA methylation,the most common form of epigenetic modifi-cations,can be influenced by the environment and dietary factors,thereby have an effect on the differentiation of CD4 +T lymphocyte,promoting the development of asthma.