Correlation of Ki-67 expression with MRS metabolism in low-and high-grade cerebral gliomas / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 281-284, 2016.
Artigo
em Chinês
| WPRIM
| ID: wpr-485652
ABSTRACT
objective:
To investigate the relationship between magnetic resonance spectroscopy (MRS) metabolism and Ki-67 expres-sion in high-(HGG) and low-grade gliomas (LGG) by analyzing Ki-67 expression and HGG and LGG metabolites.Methods:
We consid-ered 56 pathologically confirmed glioma cases in our hospital. The Ki-67 expression and the MRS metabolism parameters in the tu-mors were analyzed simultaneously.Results:
The tumor solid value of Cho was positively correlated with the Ki-67 expression level (rs=0.714, P<0.05). By contrast, the Ki-67 expression level was negatively correlated with the tumor solid value of NAA (rs=?0.708, P<0.05) in 35 cases of the LGG group. The tumor solid value of Cho was also positively correlated with the Ki-67 expression level (rs=0.624, P<0.05). By comparison, the Ki-67 expression level was negatively correlated with the tumor solid value of NAA in the HGG group (rs=?0.769, P<0.05).Conclusion:
The MRS metabolism was correlated with the Ki-67 expression in high-and low-grade gliomas.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2016
Tipo de documento:
Artigo
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