Noroviruses: Recent Updates / 대한소아소화기영양학회지
Pediatric Gastroenterology, Hepatology & Nutrition
;
: 1-7, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-48595
ABSTRACT
Noroviruses (NoVs) are one major etiologic agent in acute gastroenteritis (AGE) in all ages and are the primary cause of food-borne gastroenteritis worldwide. GII-4 NoVs has predominated since 1990s, and novel recombinant strains have been reported worldwide. Researchers face difficulties in making vaccines and therapeutic agents against NoVs due to the lack of cell culture and animal-model systems and the rapid emergence of novel variant strains. Recently, a randomized clinical trial for intranasal NoVs vaccine has been reported, which casts a light in the way of vaccine production. This review discusses the recent findings on the structure, immunity, and vaccination of NoVs.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vacinas
/
Vacinação
/
Técnicas de Cultura de Células
/
Norovirus
/
Gastroenterite
/
Luz
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Pediatric Gastroenterology, Hepatology & Nutrition
Ano de publicação:
2012
Tipo de documento:
Artigo
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