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Hepatitis C virus infection increases the incidence of intrahepatic cholangiocarcinoma: a Meta-analysis / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery ; (12): 33-36, 2016.
Artigo em Chinês | WPRIM | ID: wpr-488626
ABSTRACT
Objective A meta-analysis was conducted to evaluate the correlation between hepatitis C virus (HCV) infection and the incidence of intrahepatic cholangiocarcinoma (ICC).Methods EMBASE,MEDLINE,Web of Science,CNKI,Weipu and Wanfang databases were retrieved to identify eligible studies which were published between January 2000 and May 2015.Pooled odds ratios (OR) with 95% confidence interval (95% CI) were calculated using RevMAN 5.3.Results 14 case-control studies and 2 cohort studies were included in this study.As there was great heterogeneity among these 16 studies (Chi2 =53.18,df =15,I2 =72%,P <0.05),the random-effect model was employed.The combined risk estimates of all the studies showed a significant increase in ICC incidence with HCV infection (OR =3.96,95% CI 2.63-5.95,P < 0.05).The Begg funnel plot showed no evidence of publication bias.Conclusion HCV infection is related to an increased risk of ICC incidence.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de incidência / Estudo observacional / Fatores de risco / Revisões Sistemáticas Avaliadas Idioma: Chinês Revista: Chinese Journal of Hepatobiliary Surgery Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de incidência / Estudo observacional / Fatores de risco / Revisões Sistemáticas Avaliadas Idioma: Chinês Revista: Chinese Journal of Hepatobiliary Surgery Ano de publicação: 2016 Tipo de documento: Artigo