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Risk factors associated with early recurrence of adenocarcinoma of esophagogastric junction (typeⅠ,Ⅱ) after radical resection / 中国癌症杂志
China Oncology ; (12): 458-461, 2016.
Artigo em Chinês | WPRIM | ID: wpr-490175
ABSTRACT
Background and

purpose:

Adenocarcinoma of the esophagogastric junction (AEG) has a high incidence of early recurrence and metastasis after operation. The prognosis of AEG is poor. However, few studies have investigated the recurrence of AEG. The purpose of this study was to clarify the important clinical pathological factors affecting the early recurrence ofⅠ,Ⅱ type of AEG after operation. Thus more active treatment for patients at high risk of recurrence may improve the prognosis.

Methods:

This study retrospectively reviewed the clinical data from 145 AEG patients who underwent R0 resection during the period from Dec. 2008 to Dec. 2012. Risk factors associated with the early recurrence were analyzed.

Results:

The mean time to tumor recurrence was 25.4 months after R0 resection, and the 1-year recurrence rate was 38.6%. Univariate analysis showed that the histological grade (degree of tumor differentiation), number of positive lymph nodes, TNM stage and vascular invasion were signiifcantly related with the early recurrence (P<0.05). Logistic multivariate regression analysis showed that only histological grade and vascular invasion were independently related with early tumor recurrence (P<0.05).

Conclusion:

Histological grade and vascular invasion are independent risk factors for predicting the early tumor recurrence after R0 resection for AEG.

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Fatores de risco Idioma: Chinês Revista: China Oncology Ano de publicação: 2016 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Fatores de risco Idioma: Chinês Revista: China Oncology Ano de publicação: 2016 Tipo de documento: Artigo