The value of diagnosis and treatment of pulmonary function in children with refractory mycoplasma pneumoniae pneumonia / 国际儿科学杂志

ABSTRACT

Objective To investigate the value of pulmonary function tests in the diagnosis and treatment of children with refractory mycoplasmapneumoniae pneumonia.Methods The clinical data of 58 children with refractory mycoplasmapneumoniae pneumonia (RMPP) from May 2015 to February 2016 were retrospectively analyzed in the Department of Paediawics, Shengjing Hospital of China Medical University.They have done bronchoscopy and interventional therapy in the acute phase.Pulmonary function test was performed 24 hours before bronchoscope examinations.The endoscopic manifestation and pulmonary function data were analysed in the study.According to whether the mucosa of endoscopic manifestation is complete, fifty-eight cases were divided into mild group and severe group, record the pulmonary function indexes of each of the children.Results Severe group decreased than mild group, both of large airway pulmonary function in children with acute severe MPP (FVC, FEV1, PEF) and small airway index (FEF25, FEF50, FEF75, FEF25-75％), and the difference was significant(P ＜ 0.05).Conclusion In the acute phase, there may be different pulmonary function,such as, expressed as a normal, performance of the restrictive or obstructive ventilation dysfunction, performance ofrnixed ventilatory dysfunction, The most common one is the change of small airway function.The more severe of the endoscopic manifestation in RMPP acute phase, the more severe the same period of pulmonary function index decreased degree.The severity of RMPP in children can be predicted by the classification and severity of pulmonary function,it can be used as an important basis for the early identification of severe MPP.Pulmonary function indicators may further guide the need for bronchoscopy intervention treatment and to evaluate the curative effect.